Calotropis gigantea promotes the formation of synapses and neurites in the hippocampus

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Image: Calotropis gigantea promotes the formation of synapses and neurites in the hippocampus

(Natural News) Researchers from Dongguk University Graduate School of Medicine and Pukyong National University in South Korea investigated the neuromodulatory effects of ethanol extracts obtained from the leaves of Calotropis gigantea, a plant with a long history of use in traditional medicine. The results of their study were published in The American Journal of Chinese Medicine.

Based on these results, the researchers concluded that CGE has neuromodulatory activity and contains as yet unidentified active phytochemicals with potential nootropic, protective, or therapeutic effects on the human brain.

Journal Reference:

Haque MN, Mohibbullah M, Hong YK, Moon IS. CALOTROPIS GIGANTEA PROMOTES NEURITOGENESIS AND SYNAPTOGENESIS THROUGH ACTIVATION OF NGF-TRKA-ERK1/2 SIGNALING IN RAT HIPPOCAMPAL NEURONS. The American Journal of Chinese Medicine. 2018;46(08):1861–1877. DOI: 10.1142/s0192415x18500933