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( Natural News ) Dr. Ryan Cole has warned that the SARS-CoV-2 spike protein used in the Wuhan coronavirus (COVID-19) vaccines can cause serious damage to arteries .

The pathologist and CEO of Idaho-based Cole Diagnostics issued this warning during an appearance on “Ask Dr. Drew.” He told program host Dr. Drew Pinsky that the spike protein expresses itself in brain tissue, major organs and other areas of the body “wherever the lipid nanoparticle (LNP) distributes,” even including slides to back up his explanation.

“It does get through the blood-brain barrier,” said Cole, pertaining to the LNP. “We know the spike [protein] gets through as well. So it’ll follow the small capillaries and leak into whatever tissue it wants to.”

The pathologist then presented additional slides that showed SARS-CoV-2 spike proteins accumulating in the aorta, the heart’s main artery.

“This is something that is unusual. Usually, you’ll see this in genetic conditions where the aorta ruptures,” he pointed out. “That spike protein [is] literally causing the lymphocytes to chew a hole in the aorta. This is the biggest blood vessel in your body, coming off your heart. When that ruptures, you’re gone in minutes.”

“That’s just another example of what deposited spike protein and the induced inflammation can do,” Cole continued.

Cole and fellow program guest Dr. Kelly Victory talked about the fibrous “foot-long blood clots” taken out of autopsy patients. Brighteon.TV host Dr. Jane Ruby first broke the news of these clots after embalmer Richard Hirschmann attested to the phenomenon and presented samples of the clots to her.

“[There] is [an] unusual amount of collected proteins,” Cole said, adding that the clots are made up of “unusual combinations of proteins that make it difficult for the body to dissolve.” (Related: mRNA in COVID-19 vaccines contain FAKE URACIL which may be causing white, rubbery clots. )

Cole eventually exhorted his colleagues around the world to continue researching the long-term health effects of the experimental mRNA COVID-19 injections. COVID-19 shots can also damage organs, immune system

Prior to his appearance on “Ask Dr. Drew,” Cole had been vocal in denouncing the COVID-19 injections due to the harm they cause.

He elaborated on the harms of the spike protein during the July 2021 White Coat Summit organized by America’s Frontline Doctors in Texas. Cole gave three examples of how the spike protein damages organs: Lung cells affected by the spike protein turned purple and blue due to the excess inflammation, caused by the spike protein attaching to the lungs’ ACE-2 receptors.

Blood vessels in the brain ended up being inflamed after the spike protein crossed the blood-brain barrier.

The pericardium or heart lining suffered inflammation, which is to blame for the rise in cardiac inflammation among vaccinated younger Americans.

Later in January, Cole expounded on the COVID-19 vaccines’ impact on the immune system during an interview at the Defeat The Mandates Rally in Washington, D.C. He explained to Veronika Kyrylenko of the New American magazine that human cells have toll-like receptors (TLRs) that classify whether a foreign object in the body is harmful or not.

“When the [COVID-19] shots go into the body, they turn some of these [TLRs] off. Normally, they have to be on,” he said. TLRs deactivated by the vaccine, according to Cole, include TLR7 and TLR8 (in charge of detecting viruses) and TLR3 and TLR4 (in charge of keeping cancer under control.)

Moreover, Cole said the SARS-CoV-2 spike protein binds to the P53 gene that suppresses tumors. Its S1 subunit also links to two genes that play a role in cancer – the TMPRSS-2 gene linked to male prostate cancer and the BRCA genes linked to female breast cancer.

Watch Dr. Ryan Cole’s January interview with Veronika Kyrylenko of the New American magazine below. No compatible source was found for this media. More related stories:

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( Natural News ) The Bentex Group, an apparel and home decor design and production company, recently pulled out around 87,000 children’s clothes as the textile paint on them contained dangerous levels of lead that can poison kids.

Families were urged to immediately discard the recalled products. The kids’ clothes, which were manufactured in Egypt, were distributed by major retailers all over the United States, including TJ Maxx, DD’s/Ross, Burlington and Amazon between November 2021 and August 2022.

The recall involved children’s clothing sets in nine different Disney-themed styles, with pictures of popular characters Yoda, Mickey and Minnie Mouse and Winnie the Pooh. They were priced between $5 and $25.

Bentex issued an apology via an Instagram post: “We sincerely apologize for any inconvenience this may have caused you and appreciate your understanding in this matter.”

The New York based-company has published a list of styles included in the recall and advised all consumers to check the item and batch numbers printed on the clothing neck or side label. Affected families can contact the company and request a full refund .

According to the Consumer Product Safety Commission (CPSC), there have been no reports of injuries yet. However, the World Health Organization (WHO) warned that high levels of lead exposure in children can cause irreversible brain damage , comas, convulsions and even death.

“Children who survive severe lead poisoning may be left with intellectual disability and behavioral disorders,” the WHO added.

As per the Centers for Disease Control and Prevention (CDC), no level of lead is considered safe in children, with even low levels in blood hurting a child’s ability to learn, pay attention and do well in school. (Related: Lead is harmful at any dose; push is on to lower lead limits for Americans .)

Federal laws have banned the use of lead in paints or inks beyond trace amounts since 1978. Lead has already been replaced with other substances.

The admission that children’s clothes contained dangerous amounts of lead has infuriated parents.

“I am so angry about this. You don’t accidentally have lead products. I purchased a few of these products,” a parent posted online. “What the h*ll! How does this even happen?” said another parent.

Another one said: “So, our children are getting exposed to lead and you are just offering a $20 refund? How does that in any way make poisoning our kids right?” Sippy cups, baby bottles also contain lead

The children’s sleepwear recall came after tens of thousands of sippy cups and stainless-steel baby bottles were pulled out from the market as they contained a hazardous amounts of lead.

“Healthy and natural” baby products manufacturer Green Sprouts also announced last week that they are recalling thousands of stainless-steel bottles and sippy cups because the base of the products can break off, posing a lead-poisoning risk to children.

The Asheville, North Carolina-based company has received seven reports of the bottle’s base breaking off, exposing a solder dot containing lead , according to the CPSC recall notice .

According to CBS News , the recall involves about 10,500 cups and bottles sold at Buy Buy Baby and Whole Foods stores nationwide and online at amazon.com, buybuybaby.com and bedbathandbeyond.com from January 2020 through September 2022 for between $14 and $19.

Included in the recall were the six-ounce sprout ware sippy cup, six-ounce sprout ware sip and straw cup and the eight-ounce sprout ware straw bottle. The recalled products were all made in China, with tracking numbers 29218V06985, 35719V06985 and 33020V06985 at the bottom of the base. Consumers were urged to discard the recalled products and contact Green Sprouts for a refund or store credit.

The company further said in a separate statement that the products were sold online at babyhaven.com, drugstore.com and target.com.

Visit HeavyMetals.news for more stories related to various recalls of products that contain dangerous amounts of lead.

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Humans lose brain volume as they age, at an estimated rate of 5% per decade after age 40. But that estimate obscures the role that individual physiology plays in regards to functiona l brain aging. Utilizing sophisticated analytic tools, researchers at the Buck Institute and the University of California, San Francisco analyzed 554 patients using volumetric MRIs and blood immune samples taken over the course of a decade. The results of the study, appearing in The Proceedings of the National Academy of Sciences, show that functional brain networks are affected in different ways by aging, gender and blood immune factors.

Researchers, led by bioinformatics scientist Nikola Markov, PhD, first looked at circulating blood proteins, identifying patterns of concentrations of inflammatory proteins that increase with age, a process called “inflamm-aging.” The correlation with aging was so clear that the scientists were able to predict the chronological age of a person with striking precision just by analyzing the concentration profile of these proteins. This measure is called CyClo or a “cytokine clock.” Researchers found that both the cytokine clock and brain shrinkage follow different trajectories depending on gender, with females having a faster ticking cytokine clock even though they were more protected from brain shrinkage overall.

“ This work breaks open the black box between aging and neurodegeneration ,” says senior author and Buck Institute associate professor David Furman, PhD . “We are now able to differentiate between the brain shrinkage caused by aging versus the shrinkage caused by chronic inflammation. “Basically, if we remove the causality of time and someone has high inflammation they are on track to have a smaller brain in certain areas. In addition, by identifying inflammatory biomarkers of brain aging we have potential targets for both early diagnostics and the prevention of age-related neurodegeneration.”

The findings are based on a canonical correlation analysis. This technique allows researchers to take two sets of variables collected in the same individual and decouple the effects of these variables on a particular outcome, in this case, brain regions that are functionally connected. It also allows scientists to see in the same individual how the parameters correlate to each other. Researchers in this study analyzed three parameters – age, gender and CyClo – as well as the measures of the volume of seven functional brain networks in the same dataset. Markov says the correlation functions revealed interesting observations. The variability of chronological age measured in the population constructed the strongest correlation function with the volume of the brain networks dedicated to motor control and body sensing. The gender of the subject correlated with the visual system, ventral attention and frontoparietal networks. The biological age represented by the cytokine clock, CyClo, correlated the most with the limbic, default mode and dorsal attention network which is concerned with orienting one’s focus on a particular task.

“The significance is not just that we’ve mapped the cytokine clock to gray matter, but that we’ve done it by looking at functional networks, areas in which neurons fire together, work together, connect, and interact together.” said Markov. “We also found that although the networks are distributed across the brain, they share common vulnerabilities to the process of getting old.”

Markov says the next challenge is to understand how these immune circulating proteins directly impact the aging brain and why there are some parts of the brain that are more sensitive to peripheral inflammation than others. He says the most impactful immune proteins, or cytokines/chemokines, that showed up in blood samples include IL-6 and TNF alpha which are associated with the chronic inflammation that increases with age, as well as VEGF and PLGF, which seem to be critical for the health of the vascular system, especially the small capillaries. Researchers also identified MCP-1, Vcam-1 and Eotaxin-1 which are chemokines that change with age and attract immune cells from the blood to cross the brain blood barrier. Markov says when those chemokines cross the brain blood barrier, they cause activation of microglia, a potential initiator of the neurodegenerative process.

Going forward Furman sees two potential uses for the science: “Once we have identified that the most affected networks are also mapping to cognitive impairment in individuals who are diagnosed with Alzheimer’s or Mild Cognitive Impairment, then we have a diagnostic test. The next opportunity involves the question of whether we can modify this cocktail of cytokines to help individuals be more resilient and avoid decline in these different areas of the brain where we saw a decline in function.”

Reference: Markov NT, Lindbergh CA, Staffaroni AM, et al. Age-related brain atrophy is not a homogenous process: Different functional brain networks associate differentially with aging and blood factors. PNAS. 2022;119(49):e2207181119. doi: 10.1073/pnas.2207181119

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

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THURSDAY, Nov. 17, 2022 (HealthDay News) — Ever wonder why kids seem to pick up new knowledge and skills faster than adults?

A new study attributes the kids’ mental prowess to differences in a brain messenger called GABA.

“Our results show that children of elementary school age can learn more items within a given period of time than adults, making learning more efficient in children,” said Takeo Watanabe , a researcher and professor at Brown University.

Children have a rapid boost of GABA, an amino acid, during visual training, according to study results reported Nov. 15 in the journal Current Biology . That GABA boost lasts after training ends.

In adults, concentrations of GABA stayed constant.

“It is often assumed that children learn more efficiently than adults, although the scientific support for this assumption has, at best, been weak, and, if it is true, the neuronal mechanisms responsible for more efficient learning in children are unclear,” Watanabe said in a journal news release.

To study this issue, researchers used behavioral and state-of-the-art neuroimaging techniques on 13 elementary school-age kids and 14 adults. They found that visual learning triggered an increase of GABA in children’s visual cortex. This is an area of the brain that processes visual information.

This finding predicts that training on new items rapidly increases the concentration of GABA in children, allowing the learning to be rapidly stabilized.

Researchers did additional experiments to back this up.

“In subsequent behavioral experiments, we found that children indeed stabilized new learning much more rapidly than adults, which agrees with the common belief that children outperform adults in their learning abilities,” said researcher Sebastian Frank , now at the University of Regensburg, Germany. “Our results therefore point to GABA as a key player in making learning efficient in children.”

These findings should encourage teachers and parents to give children many opportunities to acquire new skills, whether that’s mastering math facts or learning to swim, researchers said.

The results imply that even if kids lack cognitive control or attention, they have highly efficient processing in this domain.

“Although children’s brains are not yet fully matured and many of their behavioral and cognitive functions are not as efficient as in adults, children are not, in general, outperformed in their abilities by adults,” Watanabe said. “On the contrary, children are, at least in some domains such as visual learning, superior in their abilities to adults.”

Future research should examine differences in maturation rates between brain regions and functions, the authors said. More research could also include studying GABA responses in other types of learning, such as reading and writing.

More information

The U.S. National Library of Medicine has more on GABA .

SOURCE: Current Biology , news release, Nov. 15, 2022

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( Natural News ) The beneficial biological actions of vitamin D support just about every physiological system in your body – brain health, cognitive function and nervous system health, gut health and immunity, healthy digestive system, heart health and cardiovascular function, hair and skin health, skeletal health, bone metabolism and others.

But some people are at risk of vitamin D deficiency .

These include dark-skinned people who have reduced ability to absorb ultraviolet B (UVB) rays from the sun; people who lack sun exposure (people who live in areas of high pollution, work night shifts or are homebound); infants who have not been breastfed; older adults whose skin’s ability to synthesize vitamin D decreases with age; those with health conditions that limit fat absorption; people with high levels of body fat; or people who are vegan and avoid foods that are rich in vitamin D.

Fortunately, they can use vitamin D supplements to help address that issue. Vitamin D supplements are available in capsules, sprays, chewables and drops.

Studies have identified key areas where vitamin D supplements can be of help . They are: Oxidative balance

A study in Pharmacological Research highlighted the positive effect of vitamin D supplementation on reducing oxidative stress and lipid peroxidation .

Lipid peroxidation is generally described as a process under which oxidants, such as free radicals, attack lipids, especially “good fats” or polyunsaturated fatty acids (PUFAs) that regulate hormones, transmit nerve impulses, cushion organs and store energy in the form of body fat.

In a new umbrella meta-analysis of Pharmacological Research , scientists specifically outline supplementation with vitamin D as a valid and effective solution for both combating oxidative stress and supporting pro-inflammatory actions .

A study published in Cureus demonstrated vitamin D’s ability to promote oxidative balance , also known as homeostasis. Thiol/disulfide (T/DS) homeostasis represents a promising new approach to evaluate oxidative stress. Gut microbiota

Science says immunity begins in your gut and is influenced by the thousands of bacteria, fungi, viruses and other microbes (collectively known as your gut microbiome) that live in it.

Some bacteria are associated with better health outcomes, others with poorer consequences.

In the gut microbiome, the “good bacteria” do more than just promote healthy digestion . They help keep your “bad bacteria” in check and they multiply so often that the unhealthy kind doesn’t have space to grow.

Equilibrium is what you call having a healthy balance in your gut.

A study published in Scientific Reports highlighted the positive impact of vitamin D supplementation on the richness and diversity of gut microbiota .

A separate study has also found that vitamin D supplementation increased the abundance of health-promoting bacteroidetes that provide protection from pathogens and metabolize or break down polysaccharides (starch, cellulose and glycogen) and oligosaccharides (sucrose, lactose and maltose), supplying nutrients to the host and other microbial residents of the gut.

It also decreased the abundance of bad gut microbes called firmicutes. Inflammatory response

Experts have consistently linked low levels of vitamin D to an increased risk of inflammatory diseases, such as arthritis, cardiovascular disease, multiple sclerosis and sepsis.

A study published in Biomolecules reported that recent epidemiological evidence has indicated a significant association between “vitamin D deficiency and an increased incidence or aggravation of infectious diseases and inflammatory autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis.” (Related: Vitamin D supplementation helps sufferers of chronic hives .)

Vitamin D supplementation has been used to protect against or treat some inflammatory diseases, but its effectiveness remains unclear .

Researchers recommend further studies to “determine the mechanisms of vitamin D in each disease to establish proper treatment strategies for the future.” Important things you should know before taking vitamin D supplements

A study in the Journal of Nutrition and Metabolism has found that “Australians are spending massive amounts of money on vitamin D supplements, a portion of which may potentially be unnecessary .”

If you have a vitamin D deficiency, consult a natural health practitioner to learn the appropriate dose of vitamin D you need to take daily to address your specific health needs. (Related: Vitamin D supplementation—how will it help me improve my health? )

If you are not vitamin D deficient and consume more than you need, it is possible to reach toxic levels .

High levels of calcium in your blood (hypercalcemia) can lead to calcium deposits in soft tissues, such as your heart and lungs; confusion and disorientation; harm to your kidneys (create kidney stones); or nausea, vomiting, constipation, poor appetite, weakness and weight loss.

Visit SupplementsReport.com for more stories like this.

Watch this video about vitamin D supplements and immunity . No compatible source was found for this media. More related stories: Here’s the strongest proof yet that vitamin D stops COVID in its tracks . Sources: MedicalNewsToday.com ScienceDirect.com 1 VeryWellHealth.com MindBodyGreen.com ScienceDirect.com 2 NCBI.NLM.NIH.gov 1 NCBI.NLM.NIH.gov 2 NCBI.NLM.NIH.gov 3

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( Natural News ) One of the most versatile healing spices in the world, turmeric has over 800 health benefits and is just as effective as 14 different kinds of drugs but without their adverse effects.

Turmeric has been of great interest in recent years, especially its active component curcumin, which gives it a rich golden hue. However, curcumin alone is not enough to explain the medicinal capabilities of this spice as a whole.

A study has found that another important component of turmeric , called aromatic turmerone (ar-turmerone), can be a promising candidate to support regeneration of the brain. The study by German researchers evaluated the effects of this compound on neural stem cells (NSCs), which is a subgroup of brain cells that are capable of continuous self-renewal required for brain repair.

The researchers found that when brain cells were exposed to ar-turmerone, neural stem cells increased in number, and the newly formed neural stem cells also increased the number of fully differentiated neuronal cells, which means regeneration was taking place. This effect was also observed in rats injected with ar-turmerone.

Ar-turmerone is known to reduce inflammatory response caused by activated microglia, which is associated with neurodegeneration seen in Parkinson’s disease. With this, ar-turmerone derivatives may offer new ways of treating the disease .

Parkinson’s is also a degenerative disease caused by the selective death of neurons, resulting in decreased dopamine production. While treatments such as dopamine supplements are available, there is no way to inhibit dopaminergic neurodegeneration . Previous studies also reported that the inflammatory response caused by the activation of microglia is observed in the midbrain of Parkinson’s disease patients. Thus, researchers find ar-turmerone to be a major component of turmeric that could exhibit anti-tumor and anti-inflammatory effects on the microglia.

Due to the ability of ar-turmerone to increase proliferation and mobilization of NSCs, the ability of turmeric to treat a variety of neurodegenerative diseases is huge. Alzheimer’s, dementia and other neurological disease are driven in part by neurodegenerative activity in the brain and central nervous system.

While it is still in its early stages, the potential for turmeric to mitigate or reverse some of the effects of neurodegenerative diseases is promising. Other health benefits of turmeric

Turmeric also helps the body fight foreign agents and plays a role in repairing damages. Curcumin found in turmeric is as effective as other over-the-counter drugs in bringing down inflammation to the point of reducing the pain that people suffering from arthritis can feel in their joints.

This superfood also gained popularity for its antioxidant properties, and it is believed to have antioxidant properties so powerful that it can protect the liver from getting damaged by toxins. The antioxidant properties of turmeric provide protection against the damage that can be done to the body by unstable oxygen molecules (free radicals).

The components of turmeric also have the ability to increase the secretion of bile and the production of liver enzymes, giving the spice a liver-protective effect against the toxins in the body. Moreover, animal studies showed that turmeric can lower blood cholesterol levels and prevent the coagulation of blood platelets. (Related: Comparing the effects of turmeric and turmeric-containing herbal tablets on skin barrier function .)

Indian spices like turmeric are also known to help with weight loss. It can help balance the stress hormones, which cause sudden weight gain, by reducing the formation of fat tissue. (Related: Understanding the phytochemical power of turmeric .)

Turmeric is commonly used in culinary dishes, but it can also be used as a colorant and preservative . It is safe in recommended doses, but it should not be taken in high doses by people with gallstones to avoid hindering the flow of the bile – a fluid that is made and released by the liver and stored in the gallbladder.

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( Natural News ) Research suggests that omega-3s offer many health benefits, such as improving your heart health and boosting immunity.

Detailed below are seven amazing benefits of eating superfoods or taking supplements rich in omega-3s . What are omega-3s?

Omega-3 refers to a group of unsaturated fatty acids with a specific double bond in their chemical structure like alpha-linolenic acid (ALA), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).

According to Dr. Claire Thomas, a medical doctor and clinical content lead at Evergreen Life, omega-3s are called “essential fatty acids” since the human body is unable to produce them. You can only get omega-3s through your diet.

You can boost your intake of omega-3s by taking dietary supplements and eating animal or food sources, such as:

Animal sources Anchovies (2,053 mg per 3.5 ounces (100 grams))

Caviar (6,540 mg per 3.5 ounces (100 grams))

Cod liver oil (2,438 mg per serving (1 tablespoon))

Herring (2,150 mg per ounces (100 grams))

Mackerel (4,580 mg per ounces (100 grams))

Oysters (391 mg per 3.5 ounces (100 grams))

Salmon (982 mg per 3.5 ounces (100 grams))

Plant sources: Chia seeds (5,050 mg of ALA per ounce (28 grams))

Flaxseeds (2,350 mg of ALA per tablespoon (10.3 grams) of whole seeds, or 7,260 mg per tablespoon (13.6 grams) of oil)

Soybeans (670 mg of ALA in a 1/2 cup (47 grams) of dry roasted soybeans, or 1,440 mg per 3.5 ounces (100 grams))

Walnuts (2,570 mg of ALA per ounce (28 grams), or about 14 walnut halves )

Researchers have also been studying the potential health benefits of omega-3.

According to a study published in the journal Nutrients , these nutrients may be the key factor in reducing inflammation levels, a major risk factor for several chronic diseases. Data also suggests that omega-3 could be crucial to your cardiovascular, nervous and immune systems.

Thomas said that some studies suggest that the anti-inflammatory properties of omega-3s may also offer benefits for health problems like rheumatoid arthritis and other inflammatory and degenerative joint conditions, along with inflammatory bowel diseases (IBD).

Here are seven reasons to incorporate foods rich in omega-3s into your regular diet. Omega-3s help improve brain health

Data has found that omega-3s may be essential for the proper functioning of your central nervous system, especially the brain.

The results of a study published in the International Journal of Molecular Science revealed that omega-3s may help prevent or slow the progression of neurodegenerative diseases like Alzheimer’s disease and Parkinson’s.

Experts believe there are several reasons why omega-3s are good for the nervous system.

In an article in Frontiers in Aging Neuroscience , scientists reported that omega-3s are found in abundance in the brain cell membranes. They added that the compounds may affect how neurons communicate with each other.

In another review published in the journal Nutrients , data showed that DHA is one of the key components of healthy brain and eye development. The fatty acid may also have a crucial role in mental health throughout early childhood.

Data from the article revealed that low intake of omega-3 may increase the risk of developing conditions like attention deficit hyperactivity disorder (ADHD), autism, bipolar disorder and depression.Research suggests that people who regularly consume omega-3 are less likely to experience depression. Omega-3s help boost heart health Many studies have been conducted to determine the benefits of omega-3s for cardiovascular health and many studies suggest that the compounds offer significant protective effects on the heart.The results of a major Cochrane systematic review found that omega-3s may significantly reduce the risk of dying from coronary heart disease and cardiac events. It also showed that ALA may help prevent arrhythmia.Omega-3 can boost your heart health in several ways. The compounds produce hormones that regulate blood clotting, the contraction and relaxation of artery walls and inflammation in the body. This can be beneficial for preventing heart disease as the compounds work to reduce plaque in the heart’s arteries.Omega-3s may also improve the functioning of the endothelium, the thin membrane that lines the inside of your heart and blood vessels. According to a study from the journal Atherosclerosis , the compounds may help control how much fluid is carried with the blood, and how your blood vessels dilate and constrict.Findings from research conducted on overweight patients with metabolic syndrome have revealed that the compounds may help balance blood lipids, particularly by reducing levels of LDL cholesterol or “bad” cholesterol. Omega-3s support immune health Studies have also revealed that omega-3s may have another potential benefit: boosting your immune health.Some studies suggest that omega-3s may affect the composition of your gut microbes. This can then have a positive impact on your gut health.Because your digestive system is the first line of defense against harmful microbes, omega-3 may have an indirect but wide-ranging effect on your whole immune system.In a study published in the International Journal of Molecular Sciences , researchers reported that omega-3s can stimulate the production of antibodies and regulate the functioning of white blood cells. Omega-3s support eye health Omega-3 is a significant structural component of the retina so it’s no surprise that it also has a crucial role in eye health.Your retina captures the light that enters your eye and translates it into the images you see. Without omega-3s, you may experience problems with your eyesight.Omega-3 helps optimize “the variability of photoreceptor membranes, retinal thickness, function and provides a protective role.” Additionally, healthy levels of DHA can help prevent damage from bright light exposure and oxidative stress.In research published in The American Journal of Clinical Nutrition , scientists reported that omega-3s may help prevent neovascular eye diseases like diabetic retinopathy and age-related macular degeneration. Both conditions may cause blindness and they both lack treatment options that don’t have any negative side effects. (Related: Healthy skin, vision and mood: 3 Lesser-known benefits of taking omega-3 supplements .) Omega-3s support skin health Omega-3s, especially EPA, can help promote healthier skin.Getting enough EPA helps keep your skin moisturized and also reduces the risk and effects of acne.As documented in a study published in […]

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When it comes to wellness topics, gut health often comes to mind — and it should. We’re learning that a healthy gut is an indicator overall well-being, and research has already shown that it can affect digestive, heart and brain health. Heck, what goes on in our gut community may even impact our weight and workout performances. A surprising amount of our immune system function can also be tied to gut health, also known as our microbiomes.

The human gut microbiota is a complex ecosystem that includes trillions of microorganisms on and in our intestines. And while you’ve probably heard a lot about probiotics when it comes to the microbiome, you might be less familiar with prebiotics and postbiotics — two more keys to achieving optimal gut health.

Here’s what you need to know about the “biotics” family and how to make them work harder for your best interests. Probiotics

These are living microorganisms (mainly bacteria and yeasts) found in certain foods and beverages that can take up residence in your digestive tract. It may sound creepy when you think of it that way, but as you’ve probably learned in a yogurt commercial or two, probiotics have various health benefits. They’re known for improving nutrient absorption and immune functioning, and one recent study found evidence that a greater microbiome diversity was associated with higher levels of active vitamin D — a nutrient many people are deficient in.

In general, probiotics including Lactobacillus and Bifidobacterium help maintain a healthy population of microbiota (or flora) living in the gut, positively affecting digestion and overall well-being. And for the most part, probiotics are found in fermented foods such as yogurt, kefir and kombucha. It’s thought that regularly consuming probiotics helps to replenish the beneficial microorganisms in your gut and help counterbalance any less desirable bacteria residing there.

While probiotics are little living creatures like bacteria and yeasts, prebiotics are certain components of foods including fibers, and, surprisingly, that feed and promote the growth of these healthy, or “good,” microorganisms living in our digestive tracts. In other words, prebiotics are the food probiotics require to reproduce and get to work on tasks such as . So, probiotics and prebiotics work as a team to make us healthier. This means you can take all the probiotic supplements you want and pound back all the yogurt in the refrigerated aisle, but it won’t have the maximum impact if you don’t give the probiotics a fuel source to thrive on as they take up residence in your gut.

Prebiotics are found in many whole foods you eat, such as fruits, asparagus, and .

An example of a postbiotic is the short-chain fatty acid butyrate, an energy source for the cells in your colon and what appears to be an . When you consider that inflammation is the hallmark of several chronic diseases including cancer and heart disease as well as digestive conditions like Crohn’s disease, you see why creating more of this and other short-chain fatty acid postbiotics through better nurturing our microbiome is so important.

A lack of butyrate production resulting from poor diet choices is to play a role in the development of colorectal cancer. that the short-chain fatty acid propionate that is created when microorganisms ferment certain dietary fibers can help defend against the heart-damaging effects of high blood pressure.

Short-chain fatty acids also such as that are involved in appetite and insulin secretion and can improve metabolic health. This could be one reason why high-fiber diets, which can increase postbiotic production via improved probiotic health, are especially satiating. And the short-chain fatty acid propionic acid in a way that makes it less likely to gain unwanted weight and develop type 2 diabetes.

You may have heard about the “gut-brain axis.” Well, we’re learning that postbiotic compounds are likely what mediate the impact that the microbiome has on including the development (or not) of depression and . Postbiotics including caffeic acid and ferulic acid that are produced when bacteria work on polyphenols in the large intestine could be a reason why consuming more of these antioxidants can help protect us from several conditions, including heart disease and certain cancers. They’re even believed DNA methylation, a chemical process that takes place inside your body that can alter the behavior of genes. They do so in a way that can scale back the biological clock.

Though postbiotics are a boon to your overall health, it’s still not well-understood exactly how they work. But what’s now clear is that our diet has a on microbial composition in the gut, in turn affecting a range of metabolic, hormonal, and neurological processes.

Take for instance in the where scientists determined that people whose diets scored better on the Healthy Eating Index — meaning more vegetables, fruits, whole grains and less added sugars, alcohol and solid fats — had a more potentially beneficial bacteria and lower amounts of potentially harmful bacteria in their gut microbiome. Here are some other ways to build a gut-friendly plate to get more out of these biotics.

Looks like scientists have given us a good reason to play the field when it comes to eating plants. As part of the American Gut Project, University of California San Diego School of Medicine researchers that people who ate more than 30 different types of plant-based foods per week had a greater diversity of beneficial gut microbiota than those who ate 10 or fewer types of plant foods in any given week.

On the flip side, that a meat-heavy diet, especially at the expense of plant-based foods, can shuffle around the types of microbes thriving in the gut to favor less beneficial types.

After analyzing blood and stool samples of 36 healthy adult participants, discovered that a 10-week diet high in fermented foods including yogurt, kefir, kimchi, kombucha and sauerkraut boosts microbiome diversity and decreases markers of inflammation, suggesting improved immune function.

Inulin belongs to a class of carbohydrates called fructans, which are plant carbohydrates that, because of their unique structure, resist digestion in the […]

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Recovery from depression is accelerated by Ca2+ binding to presynaptic SYT3. Credit: Nature (2022). DOI: 10.1038/s41586-022-05337-1 Scientists at Oregon Health & Science University have identified a long-sought gene-encoded protein that enables the brain to communicate a broad range of signals across gaps between neurons, known as synapses. The discovery published today in the journal Nature .

Known as synaptotagmin-3, or SYT3, the protein helps to replenish the supply of chemical neurotransmitters that carry signals between neurons.

“When brain cells are active, they release neurotransmitters to communicate with their neighbors,” said senior author Skyler Jackman, Ph.D., assistant scientist in the OHSU Vollum Institute. “If a cell is very active it can exhaust its supply of neurotransmitters, which can cause a breakdown of communication and brain disfunction.”

“It turns out that cells have a boost mode that replenishes their supply of neurotransmitters, but until now, we didn’t know the molecule that was responsible. We found that SYT3 is directly responsible for that neurotransmitter boost,” he said. “This gives us new insight about how brains can break down and fail to process information properly.”

Researchers generated “knock-out” mice that did not have the SYT3 gene. They found that those mice lacked the more robust level of synaptic transmission , compared with control mice that had the gene.

Notably, mutations of the SYT3 gene have been implicated in human cases of epilepsy and autism spectrum disorder . The research published today suggests the possibility of developing gene therapies or pharmaceutical approaches targeting SYT3, Jackman said.

“Imbalances in neurotransmitter release are the underlying causes for many neurological disorders,” said lead author Dennis Weingarten, Ph.D., a postdoctoral researcher in the Jackman lab. In the future, he said, “understanding these molecular switches—such as SYT3—is a crucial step for us to combat these diseases.”

Jackman’s lab specializes in the study of synaptic transmission. The human brain contains hundreds of trillions of synapses. Discovering the molecules that endow these specialized structures with their unique properties is essential for understanding brain function and neurological disorders.

“Synaptic transmission is fundamental for sensing our surroundings, making decisions and nearly every other feature of our inner world,” Jackman said.

Provided by Oregon Health & Science University

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