New insights into brain energy metabolism may lead to neurodegenerative disease therapies

New insights into brain energy metabolism may lead to neurodegenerative disease therapies

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists. The scientists say their findings, published in Nature , could inform new therapies…

Discovery of cellular mechanism to maintain brain’s energy could benefit late-life brain health

by University College London Deletion of A2B receptors in hippocampal astrocytes. Credit: Nature (2024). DOI: 10.1038/s41586-024-07611-w A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led…

Study finds brain stores motor memories differently based on decision uncertainty

Study finds brain stores motor memories differently based on decision uncertainty

A: Screen of the experiment, B: perturbation pattern. Credit: National Institute of Information and Communications Technology (NICT) A study published in the journal Nature Human Behaviour challenges the belief that identical physical actions are governed by the same motor memory, regardless of the decision-making…

Brain Energy Boost Mechanism Discovered

Brain Energy Boost Mechanism Discovered

Summary: Researchers identified a key mechanism that detects when the brain needs an energy boost, involving astrocytes and the molecule adenosine. This discovery could lead to new therapies for maintaining brain health and longevity, particularly in combating cognitive decline and neurodegenerative diseases. The study…

Foods Overlooked in the US May Boost Kids’ Brain Power

Foods Overlooked in the US May Boost Kids' Brain Power

A naturally-occurring nutrient found in soybeans and other legumes may support children’s cognitive abilities and attention spans, new research suggests. Read more: What Is a Health Savings Account? Soybeans are rich in a nutrient called isoflavones, which are also found in chickpeas, peanuts and…

Serotonin 2C Receptor Key to Memory

Serotonin 2C Receptor Key to Memory

Summary: Researchers discovered the serotonin 2C receptor in the brain plays a crucial role in regulating memory in both humans and animal models. This breakthrough offers insights into conditions associated with memory loss, such as Alzheimer’s disease, and suggests new treatment pathways. Mutations in…

Supranormal Hearing Achieved by Boosting Ear Synapses

Supranormal Hearing Achieved by Boosting Ear Synapses

Summary: Researchers have enhanced auditory processing in young mice by increasing inner ear synapses using neurotrophin-3. This study supports the hypothesis that synapse density impacts hidden hearing loss in humans. The findings could lead to new treatments for hearing disorders by preserving or regenerating…

Neuroscience Says 1 Simple Habit Will Help You Build Brainpower and Emotional Intelligence. Here’s How to Do It

Neuroscience Says 1 Simple Habit Will Help You Build Brainpower and Emotional Intelligence. Here's How to Do It

The science is clear: Writing is good for your brain. There are literally hundreds of studies that indicate the psychological benefits of writing. For example, Duke University researchers found that participants who engaged in a six-week program of expressive writing improved their resilience, symptoms…

Combining flavonoid with vitamin B6 may help preserve cognitive function

Combining flavonoid with vitamin B6 may help preserve cognitive function

Scientists are looking for ways to stop the degradation of vitamin B6, which may help improve brain health. Evgeniia Siiankovskaia/Getty Images A new study of mice shows that a naturally occurring flavonoid can slow down the degradation of vitamin B6 in the brain. A…

Ozempic Boost Fullness Pre-Meal via Hypothalamus

Ozempic Boost Fullness Pre-Meal via Hypothalamus

Summary: A new study shows GLP-1 receptor agonists increase pre-meal fullness by activating neurons in the dorsomedial hypothalamus. This mechanism helps prevent overeating, offering insights into obesity treatment. The research highlights how GLP-1 impacts food perception and hypothalamic responses to food cues, enhancing satiation…

CBD use during pregnancy produces strange behavior in offspring

CBD use during pregnancy produces strange behavior in offspring

CBD use during pregnancy might not be safeDepositphotos View gallery – 3 images While CBD or cannabidiol is now widely available, widely used and generally considered safe, new research has found that its use during pregnancy may produce some strange behavior in offspring and…

Next platform for brain-inspired computing

Computers have come so far in terms of their power and potential, rivaling and even eclipsing human brains in their ability to store and crunch data, make predictions and communicate. But there is one domain where human brains continue to dominate: energy efficiency. “The…

Scientists Identify Key Pathway for Brain Health Boost via Ketogenic Diet

Scientists Identify Key Pathway for Brain Health Boost via Ketogenic Diet

The ketogenic diet improves memory in aging mice by enhancing synapse function through a newly identified molecular signaling pathway involving ketone bodies, particularly β-hydroxybutyrate (BHB). Future research seeks to replicate these benefits without the diet by targeting specific pathways. Understanding these mechanisms offers new…

Science is just starting to understand the benefits of athletes putting their brains in ‘auto pilot’

Science is just starting to understand the benefits of athletes putting their brains in ‘auto pilot’

Brazil star Neymar dribbles a ball towards goal. Ricardo Rimoli/EPA Michael John O’Keeffe does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic…

Signaling pathway in brain helps maintain balance in microglia, prevent cognitive deficit

Signaling pathway in brain helps maintain balance in microglia, prevent cognitive deficit

A 3D rendered confocal image shows a single TGF- β1 knockout microglia being activated while it is surrounded by normal microglia that do not have the gene deletion. Credit: Agnes (Yu) Luo A new study led by University of Cincinnati researchers sheds new light…

Neuroscience Says This 2-Minute Brain Exercise Will Keep Your Mind Sharp and Focused All Day (and Reduce Your Stress)

Neuroscience Says This 2-Minute Brain Exercise Will Keep Your Mind Sharp and Focused All Day (and Reduce Your Stress)

The workplace is a magnet for stress and anxiety . You’ve probably come home after a bad day filled with frustration and annoyance from the day’s events, as I have. Whether it’s a missed deadline, a conflict of interest, an argument that divides the…

Resiliency shaped by activity in the gut microbiome and brain

Science News from research organizations FULL STORY A new UCLA Health study has found that resilient people exhibit neural activity in the brain regions associated with improved cognition and regulating of emotions, and were more mindful and better at describing their feelings. The same…

Unlocking the entrepreneurial brain: New perspectives on cognitive flexibility

In a recent study led by the University of Liège researchers delved into the intersection of the fields of entrepreneurship and neuroscience, looking specifically at the cognitive flexibility of habitual entrepreneurs — those who repeatedly launch new businesses — compared to less experienced entrepreneurs…

EPA proposing increased use of pesticide that’s BANNED in the EU and is 10x MORE TOXIC than other pesticides

EPA proposing increased use of pesticide that’s BANNED in the EU and is 10x MORE TOXIC than other pesticides

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Sleep is essential for memory formation

Sleep is essential for memory formation

Article image Imagine you’re a student preparing for a big exam: do you pull an all-nighter or get some rest? As many students know, lack of sleep makes retaining information difficult. Two new studies led by the University of Michigan (U-M) have recently revealed…

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