10 Phosphatidylcholine Benefits + Dosage & Side Effects

Phosphatidylcholine is a key component of our cells. Supplementing with it may improve mental, liver, and gut health, and protect nerves and improve memory. Phosphatidylcholine injections are also used for reducing fat. Read more to find out about its benefits, dosage, and side effects. Phosphatidylcholine is a molecule that contains two fatty acids attached to a glycerol backbone with a phosphate group and choline . It is found in every single cell of your body as a key component of the cell membrane [ 1 ]. Apart from its role in maintaining cell structure, phosphatidylcholine [ 2 , 1 , 3, 4 , 5 , 6 , 7 ]: is an integral component of the pulmonary surfactant – a mixture of fats and proteins lining our lungs that make it possible for us to breathe. is one of the main components of mucus that lines and protects our gut. improves communication between nerves by increasing choline and acetylcholine levels in the brain improves liver health helps breaks down fats Phosphatidylcholine levels may decrease as we age. For example, in the brain, there is a 10% reduction between age 40 and age 100 [ 2 ]. Because choline is needed to make phosphatidylcholine, low choline levels can limit its production. Choline deficiency can decrease phosphatidylcholine levels in the liver, leading to liver failure [ 8 ]. Phosphatidylcholine is also responsible for the production of very low-density lipoprotein (VLDL) [ 9 , 10 ]. Low levels of phosphatidylcholine in the brain are associated with Alzheimer disease [ 11 , 12 ]. On the other hand, high levels of docosahexaenoic acid (the fatty acid which is attached to phosphatidylcholine in the brain) are associated with a decreased risk of dementia [ 13 , 14 ]. Low phosphatidylcholine levels in certain brain areas […]

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