Photo by meo from Pexels I was looking into supplementation for enhanced cognitive function and came across this supplement called Genbrain that claims to be beneficial for thinking, memory and cognitive function.
I decided to conduct some research on the ingredients contained within Genbrain for my own peace of mind and maybe you will too after reading this post. Screenshot: Will Lawson, image from https://thegen-brains.net/ The main reason we eat food throughout the day is to help our bodies think move and function properly, Genbrain provides essential nutrients to the brain by helping to support the new generation of electrical impulses, care for strong brain cells and maintains regular levels of a neurotransmitter called Acetylcholine.
Acetylcholine is a chemical that motor neurons of the nervous system release in order to activate your muscles.
According to the company that makes Genbrain they have conducted more than 40 scientific and clinical human research studies that show the product helps enhance focus and mental stamina but I can’t confirm this without seeing them myself.
I would say that the ingredients used within Genbrain have some promising studies and research behind their benefits but although without actual peer-reviewed studies to see for myself it’s hard to back up the claims.
This product is not for use by or sale to persons under the age of 18 as specified on their website. Will this stop under 18-year-old students from experimenting with this though, well that’s yet to be determined. I can’t see any ingredients that would cause an issue.
Genbrain Proprietary Blend: Standardized 80% Genbrain 1000mg.
Smart Cleanse Detox Proprietary Blend: Flaxseed, Oat Bran, Papya Leaf Extract, Black Walnut Hull, Prune Extract, Aloe Vera, L. Acidophilus, Apple Pectin
ingredient 1 : Choline: An important micronutrient for maximal endurance and exercise playing a central role in many physiological pathways including neurotransmitter synthesis (acetylcholine), cell-membrane signaling (phospholipids), lipid transport (lipoproteins), and methyl-group metabolism (homocysteine reduction).
Google Scholar Article on Choline ( International Journal of Sport Nutrition and Exercise Metabolism Vol 18 Issue 2)
ingredient 2 : Phosphatidylserine: Phosphatidylserine is required as a cofactor for several important enzymes, such as protein kinase C and Raf-1 kinase, that are involved in signaling pathways in the brain
Google Scholar Article Phosphatidylserine ( science direct journal: progress in lipid research 2005)
ingredient 3: Ashwagandha is also known as Withania Somnifera
I found the following statement referencing improvements in memory due to Ashwagandha extracts in animals and humans.
“The drug-induced increase in cortical muscarinic acetylcholine receptor capacity might partly explain the cognition-enhancing and memory-improving effects of WS extracts in animals and in humans”
Google Scholar Article ( Peer-Reviewed Journal in the field of Pharmacognosy )
ingredient 4: Grape Seed Extract
There was a 12-week study carried out on 111 healthy older adults that found taking 150mg of grape seed extract daily improved attention, language, and immediate and delayed memory.
Specifically, the ingredient specifies red grape seed extract not actually juice from the red grapes like is mentioned in the study but the variety appears to be the same at first glance.
ingredient 5: Gastrodin
There was a study done on 200 patients post-surgery who had cardiopulmonary bypasses in which they concluded that Gastrodin is an effective and safe drug for the prevention of neurocognitive decline in patients undergoing mitral valve replacement surgery (open heart surgery) whereby during surgery your blood is circulated by a machine that takes over the work of your heart.
Newman MF, Kirchner JL, Phillips-Bute B, et al. Longitudinal assessment of neurocognitive function after coronary artery bypass surgery. N Engl J Med, 2001, 344(6):395–402
ingredient 6: Blueberry Fruit
Cognitive effects following acute wild blueberry supplementation in 21 children aged 7 to 10 found that across all measures, cognitive performance improved, following 30g of wild blueberry consumption.
Another study found that blueberry supplementation improves memory in older adults that consumed blueberries daily. At 12 weeks improved paired associate learning and word list recall was observed.
Blueberries contain anthocyanins that have been associated with increased neuronal signaling in brain centers. ingredient 7: Hops Flower Extract xanthohumol is found in Hops and is that bitterness and the flavor you get in beer. A study was conducted and it found that xanthohumol might be a potential candidate for the prevention of neurodegenerative disorders and therefore be beneficial for brain health. Screenshot: Will Lawson, image from https://pubs.acs.org/doi/abs/10.1021/jf505075n ingredient 8: Rosemary Herb Extract Rosemary herb extract has been shown to increase blood flow through the brain by inhalation through the acute ingestion of rosemary water.A study of 80 adults who were given rosemary water saw that the participants who ingested the rosemary water had interesting cerebrovascular effects (referring to blood flow to the brain).They found that the subjects drinking the rosemary water had significantly higher deoxygenated hemoglobin levels (the red protein responsible for carrying oxygen in the blood) during performing cognitive tasks than did the participants drinking water alone.The natural ingredients have known to be beneficial for cognitive function and help with brain cell health and support of new pathways within the brain.The studies and articles above for each ingredient shed some light on the benefits of this type of supplement, it will be interesting to see how many more of these brain health and performance supplements there will be in the future. Melissa Josselson is a Holistic medicine practitioner in Philadelphia, Pennsylvania and she recommends this product to her patients stating that it has been helpful for stress-related memory concerns as well as memory improvement.There are other reviews/testimonials on the Genbrain website to see, though as with any new supplement you take it will affect everyone differently.Genbrain is made in the USA and it’s also Gluten, Dairy, and Caffeine-free.It’s not FDA approved as a supplement but it is made in an FDA approved facility.It’s one of the most popular cognitive supplements on the market but whether it will have the same affect for you like others who have taken it, well that is something you can only experience for yourself. I think a product like this is worth experimenting with to see if […]