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Summary: An RNA-based therapy, COG-201, can enhance memory and reduce anxiety in animal models by targeting the serotonin 5-HT2A receptor. Scientists found that decreasing this receptor’s expression led to improved cognitive function and reduced anxiety-like behaviors in mice and rats. Notably, the therapy is…
Aging and Alzheimer’s leave the brain starved of energy. Now scientists think they’ve found a way to aid the brain’s metabolism — in mice. An experimental cancer drug that helps the brain turn glucose into energy was able to reverse memory loss in a…
Aging and Alzheimer’s leave the brain starved of energy. Now scientists think they’ve found a way to aid the brain’s metabolism — in mice. The brain needs a lot of energy — far more than any other organ in the body — to work…
Aging and Alzheimer’s leave the brain starved of energy. Now scientists think they’ve found a way to aid the brain’s metabolism — in mice. The brain needs a lot of energy — far more than any other organ in the body — to work…
Credit: Unsplash+. Alzheimer’s, Parkinson’s, and other neurological diseases can be thought of as “dirty brain” conditions, where the brain struggles to clear out harmful waste. As we age, our brain’s ability to remove toxic buildup slows down, increasing the risk of these diseases. However,…
Aging and Alzheimer’s leave the brain starved of energy. Now scientists think they’ve found a way to aid the brain’s metabolism — in mice. The brain needs a lot of energy — far more than any other organ in the body — to work…
Researchers have discovered how two brain areas, neocortex and thalamus, work together to detect discrepancies between what animals expect from their environment and actual events. These prediction errors are implemented by selective boosting of unexpected sensory information. These findings enhance our understanding of predictive…
by Sainsbury Wellcome Centre Neurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome Centre Researchers have discovered how two brain areas, the neocortex and the thalamus, work together to detect discrepancies between what animals expect from their environment and…
6 min read A long-running research endeavor reveals key chemical players that cement memories in place—and still more have yet to be discovered By Simon Makin Synapse Sebastian Kaulitzki/Science Photo Library/Getty Images The persistence of memory is crucial to our sense of identity, and…
Credit: Unsplash+ Recent research from Tokyo Medical and Dental University has uncovered a potential new approach to preserving memory and protecting against cognitive decline, a common issue as we age. The study, led by scientists including Atsuhiko Hattori, focused on melatonin, a hormone known…
2 min read Study participants felt time distortion, fewer negative thoughts and greater detachment from feelings with a noninvasive ultrasound intervention By Lucy Tu janiecbros/Getty Images Even when you aren’t doing anything, your brain is relentlessly active— daydreaming, ruminating, contemplating the past or future…
Two senior girlfriends 83 years old smoke medicinal marijuana together. One of them shows the other A promising new study suggests that long-term, low-dose THC intake may protect the brain from aging, improve cognitive function in older age, and promote overall longevity. A group…
Woman doctor examining an elderly man’s ear Hearing loss is frustrating for those who have it and for their loved ones. But recent research from Johns Hopkins reveals that it also is linked with walking problems, falls and even dementia. In a study that…
Among the many ways neuroscientists think Alzheimer’s disease may strip away brain function is by disrupting the glucose metabolism needed to fuel the healthy brain. In essence, declining metabolism robs the brain of energy, impairing thinking and memory. Against that backdrop, a team of…
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Researchers at the University of Oxford have uncovered one of the most significant data points with the COVID-19 vaccines. The COVID-19 mRNA vaccines are the sole cause of myocarditis, pericarditis and heart failure among children and adolescents. This revelation challenges the narrative pushed by…
Photo Illustration by Joules Garcia for Verywell Health; Getty Images Key Takeaways Rapid-fire, reward-driven content like social media videos can interfere with dopamine regulation and make it challenging to maintain focus on tasks lacking immediate gratification. Incorporating strategies such as regular exercise, adequate sleep,…
ARI SHAPIRO, HOST: Scientists are experimenting with a novel approach to treating Alzheimer’s disease in mice. They’re using a drug that helps the brain make energy. NPR’s Jon Hamilton says in a mouse, at least, the treatment can reverse memory loss. JON HAMILTON, BYLINE:…
Abstract. Credit: ACS Pharmacology & Translational Science (2024). DOI: 10.1021/acsptsci.4c00002, https://pubs.acs.org/doi/10.1021/acsptsci.4c00002 Bonn researchers have clarified the influence of treatment with tetrahydrocannabinol on the metabolic switch mTOR: A low-dose long-term administration of cannabis can not only reverse aging processes in the brain, but also has…
Results raise hopes that methods could be developed to detect the earliest stages of neurodegenerative disease. Facebook Email Some parts of the brain tend to atrophy and deform in concert with other regions.Credit: Zephyr/SPL An analysis of almost 50,000 brain scans 1 has revealed…